基因名:
PLK1
产品别名:
PLK; STPK13; PLK1; polo like kinase 1; polo like kinase 1; serine/threonine-protein kinase PLK1; PLK-1; cell cycle regulated protein kinase; polo (Drosophia)-like kinase; serine/threonine-protein kinase 13; 丝氨酸/苏氨酸蛋白激酶PLK1; 磷酸化丝/苏氨酸蛋白激酶Plk1;
背景信息:
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]