位置:首页 > 产品库 > 重组前胶原赖氨酸-2-酮戊二酸-5-双加氧酶1(PLOD2)蛋白
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
重组前胶原赖氨酸-2-酮戊二酸-5-双加氧酶1(PLOD2)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

重组赖氨酸羟化酶2蛋白
Recombinant PLOD2
基因名:

PLOD2


产品别名:

BRKS2; LH2; TLH; PLOD2; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; lysine hydroxylase 2; lysyl hydroxlase 2; lysyl hydroxylase 2; procollagen lysyl hydroxylase 2; procollagen-lysine 5-dioxygenase; telopeptide lysyl hydroxylase; telopeptidyl lysyl hydroxylase; 前胶原赖氨酸-2-酮戊二酸-5-双加氧酶1(PLOD2); 赖氨酸羟化酶2;


背景信息:
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2025