基因名：
POLH
产品别名：
RAD30； RAD30A； XP-V； XPV； POLH； DNA polymerase eta； DNA polymerase eta； DNA polymerase eta； RAD30 homolog A； polymerase (DNA directed), eta； polymerase (DNA) eta； xeroderma pigmentosum variant type protein； DNA聚合酶η；
背景信息：
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
