基因名:
PPAT
产品别名:
ATASE; GPAT; PRAT; PPAT; phosphoribosyl pyrophosphate amidotransferase; phosphoribosyl pyrophosphate amidotransferase; amidophosphoribosyltransferase; glutamine PRPP amidotransferase; glutamine phosphoribosylpyrophosphatate amidotransferase; glutamine phosphoribosylpyrophosphate amidotransferase; 谷氨酰胺磷酸核糖基焦磷酸酰胺基转移酶;
背景信息:
Phosphoribosyl pyrophosphate amidotransferase (PPAT) is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. The genes for PPAT and PAICS/AIRC, (a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway), are located in close proximity on chromosome 4.