基因名:
PPID
产品别名:
CYP-40; CYPD; PPID; peptidylprolyl isomerase D; peptidylprolyl isomerase D; peptidyl-prolyl cis-trans isomerase D; 40 kDa peptidyl-prolyl cis-trans isomerase D; PPIase D; cyclophilin 40; cyclophilin D; cyclophilin-related protein; rotamase D; testicular tissue protein Li 147; 亲环素D(CYP-40); 亲环蛋白(亲环素)40;
背景信息:
Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.