基因名：
MAPK3
产品别名：
ERK-1； ERK1； ERT2； HS44KDAP； HUMKER1A； P44ERK1； P44MAPK； PRKM3； p44-ERK1； p44-MAPK； MAPK3； mitogen-activated protein kinase 3； mitogen-activated protein kinase 3； mitogen-activated protein kinase 3； MAPK 1； extracellular signal-regulated kinase 1； extracellular signal-related kinase 1； insulin-stimulated MAP2 kinase； microtubule-associated protein 2 kinase； 丝裂原活化蛋白激酶1； 丝裂原活化蛋白激酶1/2； 磷酸化丝裂原活化蛋白激酶1； 磷酸化丝裂原活化蛋白激酶1/2； 磷酸化丝裂原活化蛋白激酶3； 细胞外信号调节激酶1(ERK1)；
背景信息：
The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].
