基因名：
MAPK7
产品别名：
BMK1； ERK4； ERK5； PRKM7； MAPK7； mitogen-activated protein kinase 7； mitogen-activated protein kinase 7； mitogen-activated protein kinase 7； BMK-1； BMK1 kinase； ERK-5； MAP kinase 7； MAPK 7； big MAP kinase 1； extracellular-signal-regulated kinase 5； 丝裂原激活蛋白激酶7(MAPK7)； 磷酸化细胞外信号调节激酶5； 细胞外信号调节激酶5；
背景信息：
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
