基因名：
MAP2K6
产品别名：
MAPKK6； MEK6； MKK6； PRKMK6； SAPKK-3； SAPKK3； MAP2K6； mitogen-activated protein kinase kinase 6； mitogen-activated protein kinase kinase 6； dual specificity mitogen-activated protein kinase kinase 6； MAPK/ERK kinase 6； MAPKK 6； MEK 6； SAPK kinase 3； protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)； stress-activated protein kinase kinase 3； 丝裂原活化蛋白激酶MKK6； 丝裂原激活蛋白激酶激酶6(MAP2K6)； 磷酸化丝裂原活化蛋白激酶MKK6；
背景信息：
Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
