基因名:
PRPS2
产品别名:
PRSII; PRPS2; phosphoribosyl pyrophosphate synthetase 2; phosphoribosyl pyrophosphate synthetase 2; ribose-phosphate pyrophosphokinase 2; PPRibP synthetase; PRS-II; phosphoribosyl pyrophosphate synthase II; ribose-phosphate diphosphokinase 2; testicular secretory protein Li 41; 磷酸核糖焦磷酸合成酶2;
背景信息:
Ribose-Phosphate Pyrophosphokinase 2 (PRPS2) is a phosphoribosyl pyrophosphate synthetase that belongs to the ribose-phosphate pyrophosphokinase family. PRPS2 is a homodimer. The active form is probably an hexamer composed of three homodimers. PRPS2 catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. PRPS2 catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. In addition, PRPS2 plays a central role in the synthesis of purines and pyrimidines.