基因名：
PSMA1
产品别名：
HC2； HEL-S-275； NU； PROS30； PSMA1； proteasome 20S subunit alpha 1； proteasome 20S subunit alpha 1； proteasome subunit alpha type-1； 30 kDa prosomal protein； PROS-30； epididymis secretory protein Li 275； macropain subunit C2； macropain subunit nu； multicatalytic endopeptidase complex subunit C2； proteasome (prosome, macropain) subunit, alpha type, 1； proteasome component C2； proteasome nu chain； proteasome subunit alpha 1； proteasome subunit alpha 6； proteasome subunit nu； proteasome subunit, alpha-type, 1； protein P30-33K； testicular tissue protein Li 150； 蛋白酶体PSMα1； 蛋白酶体亚基α1(PSMa1)；
背景信息：
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
