基因名：
PSMB9
产品别名：
LMP2； PRAAS3； PSMB6i； RING12； beta1i； PSMB9； proteasome 20S subunit beta 9； proteasome 20S subunit beta 9； proteasome subunit beta type-9； large multifunctional peptidase 2； low molecular mass protein 2； macropain chain 7； multicatalytic endopeptidase complex chain 7； proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)； proteasome catalytic subunit 1i； proteasome chain 7； proteasome subunit beta 6i； proteasome subunit beta 9； proteasome subunit beta-1i； proteasome subunit beta1i； proteasome-related gene 2； really interesting new gene 12 protein； 低分子质量蛋白2； 多功能肽酶2(PSMB9)；
背景信息：
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar 2010]
