基因名：
PTK6
产品别名：
BRK； PTK6； protein tyrosine kinase 6； protein tyrosine kinase 6； protein-tyrosine kinase 6； PTK6 protein tyrosine kinase 6； breast tumor kinase； protein-tyrosine kinase BRK； tyrosine-protein kinase BRK； 磷酸化酪氨酸蛋白激酶6/乳腺肿瘤激酶； 蛋白酪氨酸激酶6(PTK6)； 酪氨酸蛋白激酶6/乳腺肿瘤激酶；
背景信息：
This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation.
