基因名:
PURA
产品别名:
MRD31; NEDRIHF; PUR-ALPHA; PUR1; PURALPHA; PURA; purine rich element binding protein A; purine rich element binding protein A; transcriptional activator protein Pur-alpha; purine-rich single-stranded DNA-binding protein alpha; 嘌呤丰富元件结合蛋白A(PURA); 富含嘌呤元件结合蛋白A;
背景信息:
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]