基因名：
MAP4K2
产品别名：
BL44； GCK； RAB8IP； MAP4K2； mitogen-activated protein kinase kinase kinase kinase 2； mitogen-activated protein kinase kinase kinase kinase 2； mitogen-activated protein kinase kinase kinase kinase 2； B lymphocyte serine/threonine protein kinase； MAPK/ERK kinase kinase kinase 2； MEK kinase kinase 2； MEKKK 2； Rab8 interacting protein； germinal centre kinase (GC kinase)； 生发中心激酶MAP4K2；
背景信息：
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. [provided by RefSeq, Jul 2008]
