基因名:
RAD23B
产品别名:
HHR23B; HR23B; P58; RAD23B; RAD23 homolog B, nucleotide excision repair protein; RAD23 homolog B, nucleotide excision repair protein; UV excision repair protein RAD23 homolog B; RAD23, yeast homolog of, B; XP-C repair complementing complex 58 kDa; XP-C repair complementing protein; XP-C repair-complementing complex 58 kDa protein; RAD23同源物B(RAD23B); 紫外切除修复蛋白RAD23B;
背景信息:
hHR23A and hHR23B are the human homologues of yeast Rad23. Rad23 can interact with the Rpn10 and Rpn1 subunits of the 26S proteasome via its N-terminal Ub-like domain (UBL). Rad23 also contains two Ub-associated domains (UBA), through which it binds polyubiquitinated proteins for proteasomal degradation. In addition, Rad23 can also bind DNA repair factors to regulate nucleotide excision repair from UV damage.