基因名:
RBBP5
产品别名:
RBQ3; SWD1; RBBP5; RB binding protein 5, histone lysine methyltransferase complex subunit; RB binding protein 5, histone lysine methyltransferase complex subunit; retinoblastoma-binding protein 5; RBBP-5; SWD1, Set1c WD40 repeat protein, homolog; retinoblastoma-binding protein RBQ-3; 磷脂酰基醇蛋白聚糖-5; 视网膜母细胞瘤结合蛋白5;
背景信息:
RbBP5, retinoblastoma binding protein 5, belongs to a highly conserved subfamily of WD proteins and contains 6 WD repeats. It binds preferentially to underphosphorylated retinoblastoma protein, which is involved in the control of cell proliferation. RbBP5 is a component of the SET1 complex and of MLL containing complexes. RbBP5 is phosphorylated in response to DNA damage, probably by ATM/ATR.