基因名：
RBL2
产品别名：
BRUWAG； P130； Rb2； RBL2； RB transcriptional corepressor like 2； RB transcriptional corepressor like 2； retinoblastoma-like protein 2； 130 kDa retinoblastoma-associated protein； PRB2； RBR-2； retinoblastoma-like 2； retinoblastoma-related protein 2； 磷酸化视网膜母细胞瘤相关蛋白p130； 视网膜母细胞瘤相关蛋白p130；
背景信息：
p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and is known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.
