基因名:
REL
产品别名:
C-Rel; HIVEN86A; IMD92; REL; REL proto-oncogene, NF-kB subunit; REL proto-oncogene, NF-kB subunit; proto-oncogene c-Rel; oncogene REL, avian reticuloendotheliosis; v-rel avian reticuloendotheliosis viral oncogene homolog; V-Rel网状内皮增生病毒癌基因同源物(REL); 淋巴细胞衍生C-型凝集素; 磷酸化淋巴细胞衍生C-型凝集素;
背景信息:
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM, May 2008].