基因名：
RENBP
产品别名：
RBP； RNBP； RENBP； renin binding protein； renin binding protein； N-acylglucosamine 2-epimerase； AGE； GlcNAc 2-epimerase； N-acetyl-D-glucosamine 2-epimerase； 晚期糖基化终末产物(AGE)； 晚期糖基化终末产物(AGE)天然蛋白； 肾素结合蛋白； 肾素结合蛋白(RENBP)；
背景信息：
RENBP is a 427 amino acid protein that is a proteinaceous renin inhibitor. In inhibiting renin, RENBP forms a complex with it; a high molecular weight renin. RENBP contains a leucine zipper domain, which is essential for its dimerization with renin. RENBP can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Sequences of porcine, human and rat renin-binding proteins are highly homologous. The RENBP gene is conserved in dog, mouse, rat and zebrafish, and maps to human chromosome Xq28 between DXS52 and G6PD. Rat Renbp is located on chromosome X at Xq37 close to marker DXWox3 and falls outside the BP QTL regions on chromosome X.
