基因名:
RORC
产品别名:
IMD42; NR1F3; RORG; RZR-GAMMA; RZRG; TOR; RORC; RAR related orphan receptor C; RAR related orphan receptor C; nuclear receptor ROR-gamma; nuclear receptor RZR-gamma; nuclear receptor subfamily 1 group F member 3; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; RAR相关孤儿素受体γ(RORg); 孤儿核受体; 维甲酸相关孤儿受体γ; 维甲酸相关孤儿受体γt;
背景信息:
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].