基因名：
RPA2
产品别名：
REPA2； RP-A p32； RP-A p34； RPA32； RPA2； replication protein A2； replication protein A2； replication protein A 32 kDa subunit； RF-A protein 2； replication factor A protein 2； replication protein A 34 kDa subunit； 复制因子A蛋白2+O16484； 磷酸化复制因子A蛋白2；
背景信息：
Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
