基因名:
RRM1
产品别名:
R1; RIR1; RR1; RRM1; ribonucleotide reductase catalytic subunit M1; ribonucleotide reductase catalytic subunit M1; ribonucleoside-diphosphate reductase large subunit; ribonucleoside-diphosphate reductase subunit M1; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase, R1 subunit; 核糖核苷酸还原酶1; 核苷酸还原酶M1(RRM1);
背景信息:
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer to treatment.