基因名：
S100A4
产品别名：
18A2； 42A； CAPL； FSP1； MTS1； P9KA； PEL98； S100A4； S100 calcium binding protein A4； S100 calcium binding protein A4； protein S100-A4； S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)； calcium placental protein； fibroblast-specific protein-1； leukemia multidrug resistance associated protein； malignant transformation suppression 1； metastasin 1； murine placental homolog； placental calcium-binding protein； protein Mts1； S100钙结合蛋白A4(S100A4)；
背景信息：
S100A4 is a member of the S100 family of proteins. The S100 family is further classified as a member of the EF-hand superfamily of Ca++-binding proteins. These participate in both calcium-dependent and calcium-independent protein-protein interactions. The hallmark of this superfamily is the EF-hand motif that consists of a Ca++-binding site flanked by two α-helices (helix E and helix F) that were originally identified in a right-handed model of carp muscle calcium-binding protein. Human S100A4 is 101 amino acids (aa) in length. It contains two EF hand domains, one between aa 12-47, and a second between aa 50-85. S100A4 activity has been associated with cell transformation. It seems likely this is either coincidental, or a consequence, rather than a cause of transformation.
