基因名：
SERPINB3
产品别名：
HsT1196； SCC； SCCA-1； SCCA-PD； SCCA1； SSCA1； T4-A； SERPINB3； serpin family B member 3； serpin family B member 3； serpin B3； protein T4-A； serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3； serpin peptidase inhibitor, clade B (ovalbumin), member 3； squamous cell carcinoma antigen 1； 丝氨酸蛋白酶抑制剂B3； 鳞状细胞癌抗原1(SERPINB3)； 鳞状细胞癌抗原1(SERPINB3)真核蛋白；
背景信息：
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
