基因名：
CCL1
产品别名：
I-309； P500； SCYA1； SISe； TCA3； CCL1； C-C motif chemokine ligand 1； C-C motif chemokine ligand 1； C-C motif chemokine 1； T lymphocyte-secreted protein I-309； chemokine (C-C motif) ligand 1； inflammatory cytokine I-309； small inducible cytokine A1 (I-309, homologous to mouse Tca-3)； 嗜酸粒细胞趋化蛋白CCL1； 嗜酸粒细胞趋化蛋白CCL1前体蛋白； 趋化因子C-C-基元配体1(CCL1)；
背景信息：
Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines.CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cellfusion and virus infection.
