基因名：
CCL2
产品别名：
GDCF-2； HC11； HSMCR30； MCAF； MCP-1； MCP1； SCYA2； SMC-CF； CCL2； C-C motif chemokine ligand 2； C-C motif chemokine ligand 2； C-C motif chemokine 2； chemokine (C-C motif) ligand 2； monocyte chemoattractant protein-1； monocyte chemotactic and activating factor； monocyte chemotactic protein 1； monocyte secretory protein JE； small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)； small inducible cytokine subfamily A (Cys-Cys), member 2； small-inducible cytokine A2； MCP-1/CCL2蛋白； 单核细胞趋化蛋白1； 单核细胞趋化蛋白1(MCP1)； 单核细胞趋化蛋白1(MCP1)真核蛋白； 单核细胞趋化蛋白1蛋白； 淋巴细胞趋化因子CCL2；
背景信息：
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.
