基因名：
CCL22
产品别名：
A-152E5.1； ABCD-1； DC/B-CK； MDC； SCYA22； STCP-1； CCL22； C-C motif chemokine ligand 22； C-C motif chemokine ligand 22； C-C motif chemokine 22； CC chemokine STCP-1； MDC(1-69)； chemokine (C-C motif) ligand 22； macrophage-derived chemokine； small inducible cytokine A22； small inducible cytokine subfamily A (Cys-Cys), member 22； stimulated T cell chemotactic protein 1； 嗜酸粒细胞趋化蛋白22； 巨噬细胞来源趋化因子(MDC)；
背景信息：
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq].
