基因名:
CCL25
产品别名:
Ck beta-15; Ckb15; SCYA25; TECK; CCL25; C-C motif chemokine ligand 25; C-C motif chemokine ligand 25; C-C motif chemokine 25; TECKvar; chemokine (C-C motif) ligand 25; chemokine TECK; small inducible cytokine subfamily A (Cys-Cys), member 25; small-inducible cytokine A25; thymus expressed chemokine; 胸腺表达趋化因子; 胸腺表达趋化因子(TECK);
背景信息:
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TECK displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. TECK binds to chemokine receptor CCR9. Two alternatively spliced variants encoding two different isoforms have been identified.