基因名:
SFRP1
产品别名:
FRP; FRP-1; FRP1; FrzA; SARP2; SFRP1; secreted frizzled related protein 1; secreted frizzled related protein 1; secreted frizzled-related protein 1; SARP-2; frizzled-related protein; sFRP-1; secreted apoptosis-related protein 2; 分泌型卷曲相关蛋白1; 分泌型卷曲相关蛋白1(SFRP1);
背景信息:
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]