基因名:
SGCB
产品别名:
A3b; LGMD2E; LGMDR4; SGC; SGCB; sarcoglycan beta; sarcoglycan beta; beta-sarcoglycan; 43 kDa dystrophin-associated glycoprotein; 43DAG; beta-SG; beta-sarcoglycan(43kD dystrophin-associated glycoprotein); limb girdle muscular dystrophy 2E (non-linked families); sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); 肌聚多糖-β;
背景信息:
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.