基因名：
SGTA
产品别名：
SGT； SGT1； Vpu； alphaSGT； hSGT； SGTA； small glutamine rich tetratricopeptide repeat co-chaperone alpha； small glutamine rich tetratricopeptide repeat co-chaperone alpha； small glutamine-rich tetratricopeptide repeat-containing protein alpha； UBP； alpha-SGT； protein containing three tetratricopeptide repeats； small glutamine rich tetratricopeptide repeat containing alpha； small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha； viral protein U-binding protein； vpu-binding protein； 小谷氨酰胺三角四肽重复区蛋白α；
背景信息：
Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV-1. It also interacts with SARS-CoV Accessory Protein 7a, DNAJC5 and DNAJC5B. However, its function is not known. Since this transcript is expressed ubiquitously in various tissues, SGTA may serve a housekeeping function.
