重组唾液酸转移酶1(SIAT1)蛋白

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重组唾液酸转移酶1(SIAT1)蛋白

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Recombinant ST6GAL1
Recombinant ST6 beta-galactoside alpha-2,6-sialyltransferase 1 protein

基因名：

ST6GAL1

产品别名：

CDw75； SIAT1； ST6GalI； ST6N； ST6GAL1； ST6 beta-galactoside alpha-2,6-sialyltransferase 1； ST6 beta-galactoside alpha-2,6-sialyltransferase 1； beta-galactoside alpha-2,6-sialyltransferase 1； B-cell antigen CD75； CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase； CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1； ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1； ST6 beta-galactosamide alpha-2,6-sialyltranferase 1； alpha 2,6-ST 1； sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase)；唾液酸转移酶1(SIAT1)；

背景信息：

The ST6GAL1 gene encodes β-Galactosamide α-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galβ1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.