基因名：
SKP1
产品别名：
EMC19； OCP-II； OCP2； SKP1A； TCEB1L； p19A； SKP1； S-phase kinase associated protein 1； S-phase kinase associated protein 1； S-phase kinase-associated protein 1； OCP-2； RNA polymerase II elongation factor-like protein OCP2； SIII； cyclin A/CDK2-associated p19； cyclin-A/CDK2-associated protein p19； organ of Corti protein 2； organ of Corti protein II； p19skp1； transcription elongation factor B polypeptide 1-like； S-期激酶关联蛋白1(SKP1)； S期激酶相关蛋白1；
背景信息：
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
