基因名:
SLC2A4
产品别名:
GLUT4; SLC2A4; solute carrier family 2 member 4; solute carrier family 2 member 4; solute carrier family 2, facilitated glucose transporter member 4; GLUT-4; glucose transporter type 4, insulin-responsive; insulin-responsive glucose transporter type 4; solute carrier family 2 (facilitated glucose transporter), member 4; 葡萄糖转运蛋白4; 葡萄糖转运蛋白4(GLUT4);
背景信息:
GLUT4 is the facilitated glucose transporter expressed exclusively in adipocytes and muscle cells, and is also known as the "insulin-responsive" glucose transporter. GLUT4 translocates from an ill-defined intracellular compartment to the plasma membrane in response to insulin. The total cellular content of GLUT4 is significantly decreased in adipose cells from many patients with Type II diabetes mellitus, and animals with some types of experimental diabetes.