重组顶膜钠依赖性胆盐转运体蛋白

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重组顶膜钠依赖性胆盐转运体蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant SLC10A2
Recombinant solute carrier family 10 member 2 protein

基因名：

SLC10A2

产品别名：

ASBT； IBAT； ISBT； NTCP2； PBAM； PBAM1； SLC10A2； solute carrier family 10 member 2； solute carrier family 10 member 2； ileal sodium/bile acid cotransporter； Na(+)-dependent ileal bile acid transporter； ileal apical sodium-dependent bile acid transporter； ileal sodium-dependent bile acid transporter； sodium/taurocholate cotransporting polypeptide, ileal； solute carrier family 10 (sodium/bile acid cotransporter family), member 2； solute carrier family 10 (sodium/bile acid cotransporter), member 2；顶膜钠依赖性胆盐转运体蛋白；

背景信息：

SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.