基因名：
SLC18A2
产品别名：
PKDYS2； SVAT； SVMT； VAT2； VMAT2； SLC18A2； solute carrier family 18 member A2； solute carrier family 18 member A2； synaptic vesicular amine transporter； monoamine neurotransmitter transporter； solute carrier family 18 (vesicular monoamine transporter), member 2； synaptic vesicle amine transporter, brain； synaptic vesicle monoamine transporter, brain； vesicle monoamine transporter type 2； vesicle monoamine/H+ antiporter； vesicular amine transporter 2； 囊泡单胺转运蛋白2(VMAT2)； 脑单胺类神经递质转运蛋白；
背景信息：
Neurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism.
