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重组解旋酶样转录因子蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

重组解旋酶样转录因子(HLTF)蛋白
Recombinant HLTF
基因名:

HLTF


产品别名:

HIP116; HIP116A; HLTF1; RNF80; SMARCA3; SNF2L3; ZBU1; HLTF; helicase like transcription factor; helicase like transcription factor; helicase-like transcription factor; DNA-binding protein/plasminogen activator inhibitor-1 regulator; RING finger protein 80; RING-type E3 ubiquitin transferase HLTF; SNF2-like 3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; sucrose nonfermenting protein 2-like 3; sucrose nonfermenting-like 3; 解旋酶样转录因子; 解旋酶样转录因子(HLTF);


背景信息:
Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
 
 
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