Recombinant SMARCA4
Recombinant SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 protein
基因名：
SMARCA4
产品别名：
BAF190； BAF190A； BRG1； CSS4； MRD16； RTPS2； SNF2； SNF2-beta； SNF2L4； SNF2LB； SWI2； hSNF2b； SMARCA4； SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4； SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4； transcription activator BRG1； ATP-dependent helicase SMARCA4； BRG1-associated factor 190A； BRM/SWI2-related gene 1； SNF2-like 4； brahma protein-like 1； global transcription activator homologous sequence； homeotic gene regulator； mitotic growth and transcription activator； nuclear protein GRB1； protein BRG-1； protein brahma homolog 1； sucrose nonfermenting-like 4； 抑癌基因SNF2β；
背景信息：
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Alternatively spliced transcripts have been found for this gene, but their full-length natures have not been determined.
