基因名:
SIGLEC1
产品别名:
CD169; SIGLEC-1; SN; SIGLEC1; sialic acid binding Ig like lectin 1; sialic acid binding Ig like lectin 1; sialoadhesin; sialic acid binding Ig-like lectin 1, sialoadhesin; sialic acid-binding immunoglobulin-like lectin 1; 唾液酸粘连蛋白(SN); 唾液酸结合性免疫球蛋白样凝集素1;
背景信息:
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008].