基因名:
FSCN1
产品别名:
FAN1; HSN; SNL; p55; FSCN1; fascin actin-bundling protein 1; fascin actin-bundling protein 1; fascin; 55 kDa actin-bundling protein; epididymis secretory sperm binding protein; fascin homolog 1, actin-bundling protein; singed-like (fascin homolog, sea urchin); 磷酸化纤维束蛋白同源物1; 纤维束1; 肌动蛋白束蛋白(FSCN); 肌动蛋白结合蛋白Fascin;
背景信息:
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]