基因名:
SOD2
产品别名:
GC1; GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD; SOD2; superoxide dismutase 2; superoxide dismutase 2; superoxide dismutase [Mn], mitochondrial; Mn superoxide dismutase; epididymis secretory sperm binding protein; gastric cancer-associated lncRNA 1; indophenoloxidase B; manganese-containing superoxide dismutase; mangano-superoxide dismutase; superoxide dismutase 2, mitochondrial; 超氧化物歧化酶(SOD2); 超氧化物歧化酶2;
背景信息:
Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.