基因名:
SREBF2
产品别名:
SREBP-2; SREBP2; bHLHd2; SREBF2; sterol regulatory element binding transcription factor 2; sterol regulatory element binding transcription factor 2; sterol regulatory element-binding protein 2; class D basic helix-loop-helix protein 2; 胆固醇调节元件结合蛋白2;
背景信息:
This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants.