基因名：
SSB
产品别名：
LARP3； La； La/SSB； SSB； small RNA binding exonuclease protection factor La； small RNA binding exonuclease protection factor La； lupus La protein； La ribonucleoprotein domain family, member 3； SS-B； SS-B/La protein； Sjogren syndrome antigen B； autoantigen La； la autoantigen； lupus La antigen； sjoegren syndrome type B antigen； 干燥症SSB/La； 干燥综合征抗原B(SSB)； 干燥综合征抗原B(SSB)真核蛋白；
背景信息：
Lupus La protein (Sjogren syndrome type B antigen) (SS-B) (La ribonucleoprotein) (La autoantigen) plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs. The phosphorylation sites are at the C-terminal part of the protein. Sera from patients with systemic lupus erythematosus(SLE) often contain antibodies that react with the normal cellular La protein as if this antigen was foreign.
