基因名：
STAT2
产品别名：
IMD44； ISGF-3； P113； PTORCH3； STAT113； STAT2； signal transducer and activator of transcription 2； signal transducer and activator of transcription 2； signal transducer and activator of transcription 2； interferon alpha induced transcriptional activator； signal transducer and activator of transcription 2, 113kDa； 信号传导转录激活因子2(STAT2)； 信号转导和转录激活因子2； 磷酸化信号转导和转录激活因子2；
背景信息：
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
