基因名：
STAT3
产品别名：
ADMIO； ADMIO1； APRF； HIES； STAT3； signal transducer and activator of transcription 3； signal transducer and activator of transcription 3； signal transducer and activator of transcription 3； DNA-binding protein APRF； acute-phase response factor； 信号传导转录激活因子3(STAT3)； 信号转导和转录激活因子3； 磷酸化信号转导和转录激活因子3；
背景信息：
Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
