基因名:
STIM1
产品别名:
D11S4896E; GOK; IMD10; STRMK; TAM; TAM1; STIM1; stromal interaction molecule 1; stromal interaction molecule 1; 基质交感分子1; 基质相互作用分子1(STIM1);
背景信息:
Plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.