基因名:
AURKC
产品别名:
AIE2; AIK3; ARK3; AurC; HEL-S-90; SPGF5; STK13; aurora-C; AURKC; aurora kinase C; aurora kinase C; aurora kinase C; ARK-3; aurora 3; aurora-related kinase 3; aurora/IPL1-related kinase 3; aurora/IPL1/EG2 protein 2; epididymis secretory protein Li 90; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine-protein kinase 13; serine/threonine-protein kinase aurora-C; Aurora激酶C(AURKC); 有丝分裂激酶B;
背景信息:
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]