基因名:
TCN2
产品别名:
D22S676; D22S750; II; TC; TC II; TC-2; TC2; TCII; TCN2; transcobalamin 2; transcobalamin 2; transcobalamin-2; macrocytic anemia; transcobalamin II; transcobalamin II; macrocytic anemia; vitamin B12-binding protein 2; 转钴胺素蛋白2; 钴胺传递蛋白Ⅱ(TCN2);
背景信息:
Transcobalamin I (TCI) and Transcobalamin II (TCII) are secreted proteins belonging to the eukaryotic cobalamin transport proteins family and also to the vitamin B12-binding protein family. The genes encoding these proteins map to chromosome 11q11-q12 and 22q12.2, respectively. Transcobalamin I is a constituent of secondary granules in neutrophils, while Transcobalamin II binds cobalamin and mediates its transport into cells. These plasma proteins are expressed in various tissues and secretions.