基因名:
TDO2
产品别名:
HYPTRP; TDO; TO; TPH2; TRPO; TDO2; tryptophan 2,3-dioxygenase; tryptophan 2,3-dioxygenase; tryptophan 2,3-dioxygenase; tryptamin 2,3-dioxygenase; tryptophan oxygenase; tryptophan pyrrolase; tryptophanase; 色氨酸-2,3-双加氧酶(TDO); 色氨酸2,3双加氧酶;
背景信息:
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]