基因名:
TERF1
产品别名:
PIN2; TRBF1; TRF; TRF1; hTRF1-AS; t-TRF1; TERF1; telomeric repeat binding factor 1; telomeric repeat binding factor 1; telomeric repeat-binding factor 1; NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; telomeric protein Pin2/TRF1; telomeric repeat binding factor (NIMA-interacting) 1; 端粒体复制结合因子1; 端粒重复结合因子1(TERF1);
背景信息:
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq].